2282 Results
Addressing inequities in colorectal cancer outcomes
Inequities in colorectal cancer have been known for decades but little progress in addressing these has been made.Funding proposalsUsing an imaging drug to reduce brain metastases
Two-thirds of cancer deaths occur when cancers spread around the body. When cancer spreads to the brain (brain metastases), patients have a dismal prognosis with the metastases challenging to treat.Funding proposalsCopy-number variation: a source of missing heritability for heart failure?
Heart failure is a leading cause of hospitalisation in adults over 65 years and one in four patients die within 1 year. Any condition that damages the heart can cause heart failure.Funding proposalsHarnessing tears for diagnosing Pacific PINK1 and idiopathic Parkinson’s disease
Our tears contain tiny biological clues that can help detect diseases early.Funding proposalsUnderstanding occupational health and hazard exposures in rural Pacific meatworkers
Meat processing is a hazardous work environment with multiple health risks. Pacific peoples are overrepresented in this industry with high rates of injury and work-related harm.Funding proposalsA matauranga Māori approach to Health Technology Assessment
This research explores an innovative and novel approach to Health Technology Assessment. This exploratory project aims to draft a new Health Technology Assessment framework inclusive of Equity measures.Funding proposalsThe Pasifika Health Psychology Consultation Guideline
Pasifika communities in Aotearoa New Zealand face longstanding inequities in both mental and physical health outcomes. Consultation with Pasifika is vital in conducting culturally safe and responsive health and psychology research.Funding proposalsHe Kākano i Ruia: Cultivating mental resiliency through the Māori All Blacks
This cross-disciplinary rangahau explores the mental health and wellbeing of Māori All Blacks players and staff across a full representative season.Funding proposalsHe Iti Rearea Kahikatea ka Taea
He Iti Rearea Kahikatea ka Taea (He Iti Rearea) is a kaupapa Māori research training course.Funding proposalsNon-traumatic dental presentations (NTDPs) to Tairāwhiti Hospital ED, 2024
More than half of the people in Tairāwhiti are of Māori whakapapa. People in Tairāwhiti with severe tooth pain and gum swelling go to the hospital. They are seen in the emergency department (ED) because there is no hospital dental department.Funding proposalsEvaluating Online Vaccine Resources for Informed Decision-Making by Hapū Māmā
This summer studentship is part of a wider HRC-funded kaupapa Māori study that supports hapū māmā to make informed decisions about vaccination during pregnancy.Funding proposalsTakatāpui Resilience and Joy: A Kaupapa Māori Literature Review
This kaupapa Māori informed literature review seeks to address a critical gap in understanding Takatāpui (Māori LGBTQIA+) health and wellbeing.Funding proposalsTargeting glutamatergic excitation to treat menstrual cycle-linked seizures
For around 40% of women with epilepsy, the menstrual cycle increases their seizure frequency two-fold or more. Building on my past studies, in this project I propose a clinical trial of memantine in the treatment of females with epilepsy.Funding proposalsDeveloping enzymatic tools to enable next-generation cell-targeting therapies
Advances in disease modelling and cell-based therapies hinge on precisely controlling which cells are eliminated and which are protected.Funding proposalsDecoding host-fungal interactions to improve respiratory health outcomes
We breathe over 10,000 litres of air each day, exposing our lungs to thousands of microbes, including fungal spores. Each microbial encounter leaves a lasting imprint on the lungs, shaping how our immune system responds to future infections and allergens.Funding proposalsIdentity intersections and wellbeing among takatāpui in Aotearoa
This research explores how the intersections of Māori and takatāpui identity/shape sexual health and holistic wellbeing in Aotearoa.Funding proposalsEvaluating the impact of increased adiposity on assisted reproduction outcomes
Infertility affects many families in Aotearoa, and Pasifika experience some of the highest rates, yet they are among the least likely to access fertility treatment.Funding proposalsDeveloping models of theca cell differentiation to understand ovulation failure
Ovulation is the process where a mature egg is released from the ovary and is essential for fertility. However, surprisingly little is known about a cell type integral to this process called the theca cells.Funding proposalsPaediatric neurology clinical trials
Neonatal seizures affect one in every 300 newborns. Survivors have high rates of permanent neurodevelopmental disability and epilepsy. Faster detection and better treatments could improve these outcomes.Funding proposalsPrimary care model to improve eye health outcomes for whānau with diabetes
The placement research activity will focus on developing and evaluating a model of diabetes eye care services from a primary care perspective.Funding proposalsAn assessment of Hua Oranga as an outcome tool for Māori with spinal cord injury
This research study explores a new way to measure Quality of Life (QoL) for Māori people after a spinal cord injury (SCI). Existing QoL measures often miss the specific cultural values and concepts of wellbeing that are important to Māori.Funding proposalsFILTER-F: Surgical site infection and intravenous medication filtration
Surgical site infection (SSI) is a serious complication after cardiac surgery, leading to longer hospital stays, worse recovery and higher costs. This research will lay the groundwork to explore whether a low-cost intravenous filter can reduce that risk.Funding proposalsUnderstanding SABA reliever use in those prescribed an AIR
Asthma treatment in New Zealand has changed significantly in recent years, in response to clinical trials which have shown that anti-inflammatory reliever therapy using the budesonide/formoterol two-in-one inhaler, also known as the ‘anti-inflammatory reliFunding proposalsExploring digital enablement opportunities in delivery of prevention services
This research aims to explore opportunities for digital enablement of services focused on prevention using the South Auckland Living Smokefree Service as an example. Assisting people and families to stop smoking is crucial for preventing health loss.Funding proposalsCOVID-19 antivirals: who is missing out?
SARS-CoV-2 still poses a real threat to public health, with hospitalisations in New Zealand (NZ) due to COVID-19 outnumbering all other infectious diseases.Funding proposalsNesian narratives: Bridging knowledge through digital and community design
This application proposes the design and visual illustration of the Nesian Narratives Toolkit—a culturally grounded educational resource aimed at strengthening Pacific child wellbeing.Funding proposalsThyroid dysfunction in infancy: detection, aetiology and clinical safety
Thyroid hormones are crucial for growth and brain development, and it can be difficult to interpret results during the early neonatal period.Funding proposalsEvaluating risks and economic costs of respiratory illness in cerebral palsy
One child is diagnosed with cerebral palsy (CP) every 4 days in New Zealand (NZ). Early life events e.g. prematurity, hypoxia, infection, all lead to CP, with delayed motor skills and lifelong physical disability.Funding proposalsDeveloping a targeted plasma DNA methylation panel for prostate cancer detection
Aotearoa New Zealand (NZ) has one of the highest prostate cancer incidence and mortality rates worldwide and much poorer outcomes in Māori communities.Funding proposalsThe role of continuous glucose monitoring in diabetes self-management education
Prediabetes and type 2 diabetes are growing health challenges in Aotearoa New Zealand, disproportionately affecting Māori and Pasifika, and account for a significant proportion of the healthcare budget.Funding proposalsExperiences of mothers and their families during postnatal psychiatric illness
Suicide is a leading cause of death for new mothers in the months after childbirth worldwide. New Zealand (NZ) and United Kingdom (UK) families reel from these deaths and the impacts that flow from poor mental health.Funding proposalsImproved follow-up care after chest pain assessment in the emergency department
Many people who visit emergency departments in New Zealand with chest pain are tested for heart attacks using a blood test called troponin.Funding proposals