3304 Results
Neurocardiac coculture approach to the long QT syndrome
The long QT syndrome (LQTS), an inherited heart disease, is the most common cause of unexplained sudden death in young New Zealanders.Funding proposalsKei roto tō tātau rongoā: A community/whānau-based approach for wellbeing
Whānau Māori live with family violence and have mokopuna (babies and children) removed for child maltreatment at significantly higher rates than non-Māori families. For these whānau, the health and wellbeing consequences are immense and long-term.Funding proposalsUnderstanding how heparan sulfate mimetics control neuroinflammation
To protect the brain from the damaging effects of immune cells, entry of these cells into the brain is severely restricted. However, entrance is not forbidden but is controlled by cellular networks such as the blood-brain barrier and the choroid plexus.Funding proposalsIntersectional ethnic minority youth: harnessing creativity for health gains
Young people belong to multiple shifting identities.Funding proposalsSelf-management of long-term conditions for Pacific people
Self-management is a time consuming, continuous challenge, with little research specific to Pacific people. This project will explore the key cultural elements that assist Pacific people in managing long-term health conditions.Funding proposalsDeveloping a supported playgroup for children of Pacific families
This project aims to promote development and maximise beneficial childhood experiences/support for the Pacific community by identifying key components of the playgroup experience that are culturally important to Pacific peoples through qualitative intervieFunding proposalsReducing health inequalities: Pacific experiences in the DHB system
The principal purpose of my research was to analyse the Pacific health sector experience during the health reforms that began in the year 2000, which established District Health Boards (DHBs) and required, for the first time, an explicit focus on reducingFunding proposalsMe'akai, Suka mo e Mo'ui Lotolu (Food, diabetes and total wellbeing)
The high prevalence of diabetes among Tongans in New Zealand is due to lifestyle changes and acculturation. Talanoa and the hermeneutic phenomenology approach has captured the lived experiences of Tongans with diabetes.Funding proposalsTalanoa 'o e Me'akai mo e Suka
Food is to be enjoyed rather than a treatment for diabetes. Sai ange mate makona (better to die in full stomach). Kai pe ke fakahounga'i si'enau hela (eat to appreciate/respect their effort to provide food).Funding proposalsAetiology-focused treatment: a new paradigm for empiric pneumonia treatment
New Zealand has the highest rate of Legionnaires’ disease (pneumonia caused by Legionella bacteria) in the world. As a notifiable disease and the most common cause of pneumonia during peak season, Legionella requires specific antibiotic treatment.Funding proposalsPasifika intervention to increase uptake of urate-lowering therapy for gout
Gout is a painful form of arthritis caused by high urate in the blood, crystallising in joints. First-line treatment involves taking long-term, urate-lowering therapy (ULT) to prevent gout flares.Funding proposalsTargeted drug delivery to the stomach
Cancer drug therapy must find a balance between the inhibition of tumour growth and the unavoidable side effects of treatment.Funding proposalsRCT budesonide-formoterol vs salbutamol reliever therapy in preschool asthma
Asthma is the most common chronic disease of childhood. The greatest burden is in children aged <5 years. The evidence base for the treatment of childhood asthma is considerably less than for adult asthma.Funding proposalsKaitiaki's perspectives of adolescent rehabilitation from ACL injuries
New Zealand has the third-highest annual incidence rate of Anterior Cruciate Ligament (ACL) and increasing injuries and ACL reconstructions in our adolescents.Funding proposalsTackling ableism to remove barriers to participation in sport and recreation
Being physically active – and remaining so across the life-course – is vital for physical and psycho-social health and wellbeing. Disabled young people have lower physical activity levels than non-disabled peers.Funding proposalsLymphocyte specific kinase inhibitors for controlling immunotherapy toxicity
Turning on a type of white blood cell called T-cells to seek out and kill cancer cells is a major advance in cancer therapy.Funding proposalsKnowledge, attitudes and practices of COVID-19 among Pacific people in Aotearoa
Ethnic minority groups throughout the world were more affected by COVID-19 than dominant populations.Funding proposalsA device for monitoring visual acuity progression in young children at home
Amblyopia or lazy eye is a condition that, if left untreated, causes lifelong visual impairment, reduced quality of life, and doubles the lifetime risk of legal blindness.Funding proposalsOptimising the potential benefits of lung cancer screening in Māori in New Zealand
Māori develop lung cancer earlier with higher incidence and mortality than non-Māori. Screening has been shown to reduce mortality through earlier diagnosis and is now recommended for high risk populations in both the USA and Europe.Funding proposalsMeasuring the health state preferences of New Zealanders
Measuring the health benefits of treatments consistently across a wide range of health conditions is crucial for informing resource allocation across the health system.Funding proposalsTe Pu Korokoro: Improving the physical health of Māori with psychosis
People with psychosis have a considerably shortened life expectancy of up to 20 years when compared to the general population.Funding proposalsVisualising and controlling the cause of hot flushes at menopause
Approximately 70% of women experience hot flushes during menopause. These often debilitating symptoms persist for 7 years on average, markedly reducing quality of life.Funding proposalsA novel brain pathway involved in pathogenesis of obesity and type-2 diabetes
New Zealand has high rates of obesity and its associated complications such as type-2 diabetes (T2D). Māori and Pacific people are disproportionately affected by these disorders, with the prevalence of T2D two to three times higher than Pakeha.Funding proposalsPasifika B4 School: Exploring child and family wellbeing
Pacific children experience the lowest rates of timely completion of Well Child assessments, including substantial shortfalls in the B4 School Checks.Funding proposalsHarnessing lung resident immune cells for mucosal vaccines
Protection against respiratory pathogens, including influenza virus are initiated by the mucosal immune system. However, most licenced vaccines are administered parenterally and are largely ineffective at inducing mucosal immunity.Funding proposalsPacific identity and spirituality in mental health and wellbeing
The purpose of this research study is to explore key Pacific concepts, models, and approaches that encompass Pacific identity and spirituality in mental health and wellbeing.Funding proposalsTe Kura Mai i Tawhiti - kaupapa Māori early years provision and health outcomes
Early years interventions for pre-schoolers have been found to improve health throughout life. However, what is largely missing are early years programmes demonstrated to improve outcomes of importance for the health and wellbeing of Māori.Funding proposalsExploring the understanding and expression of anger among Pasifika youth
Research has shown that individuals who experience chronic intense anger or have difficulty regulating their expression of anger can experience significant psychological distress and functional impairment.Funding proposalsTaufa’s 5G’s model – the intra-ethnic variations among Tongan teenage mothers
Taufa's 5G model was developed in response to my PhD on Pacific teenage pregnancy in New Zealand where intra-ethnic variations among Tongan teenage mothers were explored.Funding proposalsWhanaungatanga and association with health outcomes, health literacy and access
Secondary data analysis using Youth2000 survey series, a national survey of the health and wellbeing of secondary school students aged 12 to 18, to identify how (1) whanaungatanga may act as a protective factor for rangatahi (2) whether whanaungatanga actsFunding proposalsTe Korowai Hauora o Hauraki response to mental health needs in rangatahi
The purpose of this piece of research will be to investigate and analyse how Te Korowai Hauora o Hauraki responds to the mental health needs of rangatahi.Funding proposalsExtracellular vesicles as prognostic markers for endometrial cancer
Endometrial cancer is the most common gynaecological cancer in New Zealand, and incidence rates are rising, particularly in younger women.Funding proposals