3389 Results
Novel targets within the carotid body for treating cardiometabolic disease.
The number of New Zealanders affected by the cardiometabolic disease is projected to nearly double in next decade, exacerbating already existing health inequities in Māori and Pacific people.Funding proposalsSalivary MicroRNAs as Prognostic biomarkers of heart disease
Patients with chronic ischaemic heart disease (IHD) require regular follow-up to monitor the progression of the disease and response to treatment.Funding proposalsThe gut gets going
The gut is an organ that is sensitive to its manual handling during surgery and to overall body health status. One of its responses to local insult or illness is to stop moving, a state that is called ileus.Funding proposalsGlucoregulation by leptin: The missing piece to the puzzle of tissue repair?
It is well known that individuals with obesity or type 2 diabetes have severely impaired tissue repair, but the underlying mechanisms are largely unknown.Funding proposalsPumping gas the right way
Inability to sufficiently breath and to provide the body's oxygen need is very common in a wide range of critical illness states. More recently high profile illness states such as covid-19 have seen a dramatic rise in the use of mechanical ventilation.Funding proposalsNovel approaches to support patients in acute settings
The current interest in respiratory failure due to COVID-19 has focused interest in solutions to improve outcomes when patients are on prolonged periods of oxygen supplementation and ventilation.Funding proposalsThe warfare between bacteria and bacteriophage, its benefits to humankind
The aim of the project is to identify natural antiviral compounds against human viruses by activating the bacterial immune system.Funding proposalsHRC Update 19 May 2022
NewsRaising the bar - home edition (online)
"The untapped potential of DNA to personalise your healthcare and extend your life"EventTransforming Mental Health Conference (live or online)
At a crucial moment for the health system in New Zealand, the Transforming Mental Health Conference will explore how to transform the planning, funding, delivery and management of mental health services.EventA nationwide strategy to improve lung cancer outcomes with molecular testing
Lung cancer mortality is particularly high in NZ, with stark inequities adversely affecting Māori and Pasifika. As poor outcomes result from diagnosis at late stage, earlier detection would improve patient survival.Funding proposalsCumulative impacts of air pollution exposure on adult physical and mental health
Air pollution is recognised as a cause of morbidity but its longer-term and cumulative effects on health are less established. In New Zealand, persistent health inequities exist for Māori who are exposed to poorer environments than non-Māori.Funding proposalsImproving population health through education of the innate immune system
Reduced exposure to microbial products and pathogens in early life through increased hygiene and urbanisation has been associated with increased prevalence of disorders related to immune dysfunction, including inflammatory and allergic diseases and autoimmFunding proposalsDevelopment of an ultrasound responsive implant to treat spinal cord injury
Spinal cord injury is devastating and incurable with a relatively high prevalence in New Zealand. Growth factors are known to help recovery, although it is not currently possible to deliver appropriate amounts to the site of injury.Funding proposalsA data-driven approach to predicting asthma attacks in Aotearoa
Asthma is one of the most common long-term conditions in New Zealand (NZ), affecting 1 in 5 children and 1 in 8 adults. Asthma attacks are the leading cause of asthma deaths, placing a significant burden on our health system.Funding proposalsExploring the role of the inflammasome pathway in diabetic retinopathy
Diabetes is one of the most common health problems in New Zealand affecting over 250,000 New Zealanders. It is associated with several complications, one of which is diabetic retinopathy (DR), a chronic disease that can lead to vision loss.Funding proposalsModelling procalcitonin for bacterial infections in intensive care
Over 14,000 patients are admitted to intensive care each year in Aotearoa. About half will develop infections.Funding proposalsOlder informal caregiver experiences following the COVID-19 pandemic in Aotearoa
Informal caregivers play a vital role in the healthcare and social services in Aotearoa. However, their unpaid labour is undervalued, and challenges associated with caregiving during the pandemic are understudied.Funding proposalsTreating gastric cancer according to its biology
Cancers originating from the same anatomical location often display distinct characteristics, which influence their interaction with the immune system, the success of treatments and patient survival.Funding proposalsInvestigating fibroblast influence on the gastric cancer microenvironment
Gastric cancer is more than one disease, having two main subtypes that show markedly different appearances microscopically, yet it is treated as one disease.Funding proposalsInvestigating the diet-microbiome connection in paediatric coeliac disease
Coeliac disease is an autoimmune disease that occurs in 1/82 Cantabrians - one of the highest rates in the world, making Canterbury an interesting place to study coeliac disease.Funding proposalsMenstrual cycle status and iron deficiency diagnosis in healthy females
This project aims to examine the changes in menstrual cycle status, primarily bleeding characteristics in healthy regularly menstruating premenopausal females in response to psychological stress and dietary intake.Funding proposalsStudy to determine long-term effects of air pollution on health
A new study into the cumulative effects of air pollution on New Zealanders’ physical and mental health will kick off next month in Christchurch using data from one of New Zealand’s longest-running longitudinal studies.NewsHRC boosts access to community research funding
With its revamped Ngā Kanohi Kitea Community Advancement Fund, the Health Research Council is making it easier for communities to undertake research and address self-identified health/hauora needs and priorities.NewsImplementing effective lifestyle treatment for T2 Diabetes in primary care
Type 2 Diabetes (T2D) and prediabetes (PD) are a major challenge for the NZ health system. Disproportionately affecting Māori and Pacific people, it is a leading driver in health inequalities.Funding proposalsDelivering optimal weight gain advice to pregnant women (DOT) study
Unhealthy weight gain in pregnancy is common in Aotearoa/New Zealand (up to 70% of pregnant women). It increases the risk of adverse outcomes e.g. gestational diabetes and large for gestational age babies.Funding proposalsMeasuring the impact and social value of Turanga Health's services
How can Māori health providers measure the impact and social value of their activities in complex environments? Can a tool such as Social Return on Investment (SROI), developed overseas, be useful in a kaupapa Māori setting?Funding proposalsHRC Update 17 June 2022
NewsMāori-led research team to undertake real-time research on key Māori health policy
An independent Māori-led research team has been awarded $1.5M by the Ministry of Health and Health Research Council to track the implementation and progress of the government’s Whakamaua Māori Health Action Plan 2020–2025.NewsPae Ora - collaborations in action
We will undertake a mixed-methods evaluation of Whakamaua: Māori Health Action Plan 2020-2025, which will embed Te Tiriti o Waitangi and Mātauranga Māori to ensure translational research that addresses the outcomes, objectives and potential future directioFunding proposalsStudy to develop safer alternative to opioids part of more than $78M allocated to health research
A research team who have developed a suite of non-addictive drug compounds to treat pain have received one of 53 HRC grants in a $78.92 million funding allocation for new and innovative research into some of New Zealand's most pressing health…NewsThe impact of nitrate in drinking water on preterm birth
This research will investigate the association between nitrate in drinking water and preterm births.Funding proposals