3304 Results
Is elevated cardiac fibrosis in Pacific patients associated with reduced klotho?
Diabetes is known risk factor for development of heart disease, and Pacific people are more likely to develop diabetes (11.1%) compared to Maori (7.6%) and NZ European (4.9%).Funding proposalsCirculating miRNAs in maternal blood as biomarkers for preterm birth
Pregnancy complications, including preterm birth (8% of births in New Zealand), have significant health impacts on the mother and baby, in addition to significant healthcare costs.Funding proposalsSystematic Review and Clinical Audit of Non-Communicable Diseases in Rarotonga
The aim of this project is to determine the burden of non-communicable diseases (NCDs) in the Cook Islands by conducting a systematic literature review of NCDs in the Pacific and undertaking a clinical audit of NCDs in the Cook Islands.Funding proposalsThe Immunogenetics of Rheumatic Fever and Rheumatic Heart Disease
Acute Rheumatic Fever (ARF) can develop after infections with Group A Streptococcal (GAS) bacteria. If untreated, this can lead to Rheumatic Heart Disease (RHD).Funding proposalsLongitudinal quantification of unique Escherichia coli strains
New Zealand has some of the highest cases of eczema and skin infections in the developed world. The microbiome plays a critical role in the development of eczema in early childhood.Funding proposalsWhat are the reformulation preferences of children and young people receiving regular BPG injections
Acute Rheumatic Fever (ARF) is an autoimmune condition caused by untreated Group A Streptococcal (GAS) infection of the throat and possibly skin. Multiple or sever attacks of ARF can cause permanent heart damage known as Rheumatic Heart Disease (RHD).Funding proposalsOptimising preschool obesity intervention: the Whānau Pakari preschool project
Whānau Pakari (WP) aims to improve mainstream service provision for Māori. It has become the assessment/intervention service model in Taranaki for children/adolescents with obesity.Funding proposalsTane Maori access to and perceptions of primary care
This study will be investigating the perceptions of Māori key informants regarding engagement and access to primary health care services by Tane Māori.Funding proposalsPOIS-10 Māori: Outcomes and experiences in the decade following injury
Māori experience injury and disability inequities. Our Prospective Outcomes of Injury Study (POIS) has investigated a range of Māori post-injury outcomes to two years post-injury, adding to a current knowledge gap.Funding proposalsDeveloping optimal strategies to support smoking cessation among roll your own (RYO) tobacco users
New Zealand has among the highest rates of roll your own (RYO) tobacco use internationally; RYO causes particular harm to Māori, young adults and people experiencing lower prosperity.Funding proposalsReducing the burden of Metabolic disease in Maori
Metabolic disease is twice as likely to affect Māori compared to other populations in New Zealand and affects this population at an earlier age, leading to greater morbidity, disability and lower life expectancy.Funding proposalsTargeted therapeutic mild hypercapnia after resuscitated cardiac arrest
Cardiac arrest is a major health problem in New Zealand - a common and catastrophic event effecting around 4500 per annum. Of the 27% of people who experience a cardiac arrest and survive to hospital admission, only 29% survive and leave hospital.Funding proposalsMāori rangatahi suicide - informant perspectives on determinants and solutions
Suicide statistics for rangatahi Māori are stubbornly high and show no signs of retreat. Although there are numerous strategies and initiatives, there still remains a need for more research into the driving forces behind suicide, especially in youth.Funding proposalsWhānau Manaaki : Methamphetamines- a strength based community approach
During our research consultations in Te Wairoa about an expanded maternal health pathway to improve infant and whānau (Māori family) health and wellbeing, the issue of methamphetamine (‘P’) use in the community was often raised.Funding proposalsProspective Outcomes of Injury Study: 10 years on (POIS-10)
In New Zealand (NZ), injuries are prevalent, costly, and burdensome – causing 34% of disability.Funding proposalsDoes a brief sleep intervention in infancy have long-term health benefits?
Given that one in three New Zealand children are overweight or obese, research aiming to address the global obesity pandemic has increasingly focused on opportunities for prevention in early life, particularly in the ‘first 1000 days’ (from conception to 2Funding proposalsVitamin and mineral supplements among Pacific People
Vitamins and minerals are necessary for physiological functions and body processes. It is understood that eating a wide variety of fresh foods is the best way to ensure necessary nutrients are consumed.Funding proposalsUnderstanding scabies prevalence to improve the health of Pasifika/Māori kids
Our aim is to undertake a designed survey of scabies prevalence of Auckland children in educational institutions. This will be the first such survey for over 30 years.Funding proposalsClimate change and mental wellbeing: The impacts on Pacific peoples
Much of the health research on climate change in the Pacific is dominated by physical health problems; only recently have the mental health impacts of climate change been recognised.Funding proposalsDissecting the role of glial lysosome function in neurodegeneration
Maintaining a healthy brain requires a fully functional cellular recycling system. The lysosome is the final destination of cellular waste and its dysfunction is a common feature of many neurological diseases including Alzheimer’s and Parkinson’s disease.Funding proposalsPatterns of recovery from concussion in children and adolescents
Concussion is a common injury during childhood and adolescence. For many, symptoms resolve quickly but up to a third experience persistent symptoms.Funding proposalsA neural circuit to suppress stress in motherhood
Prolactin is a hormone which drives many neural adaptations during pregnancy and lactation, including the suppression of behavioural and endocrine stress responses.Funding proposalsReadying next-generation antifungals for drug development
Opportunistic invasive fungal infections (IFIs) carry high morbidity and mortality for those with co-morbidities, especially the immunocompromised, such as transplant and AIDS patients.Funding proposalsBiomarker-guided secondary prevention post-acute coronary syndromes: A randomised controlled trial
Recurrent clinical events remain common among patients following an acute heart attack.Funding proposalsEnrichment of community health through targeted social protection strategies
This project investigates the socio-economic and cultural drivers of poor health amongst the Pacific population and identifies the shortcomings of existing traditional and formal social protection strategies to address these drivers.Funding proposalsA novel genetic mechanism in Acute Myeloid Leukaemia
Acute myeloid leukaemia (AML) is an aggressive cancer of the bone marrow with an overall survival of ~30%. Outcomes for older patients are especially poor, with cure rates of only 10-15%.Funding proposalsQualitative analysis of Māori patients' primary health care experiences
The purpose of this research is to assess the experiences of Māori patients enrolled at Mataora, a new Very Low Cost Access (VLCA) Māori health provider in South Dunedin.Funding proposalsInternational case-control study of sudden unexpected death in epilepsy
A case-control study of sudden unexpected death in epilepsy (SUDEP) will be undertaken.Funding proposalsHealth and equity impacts of Te Ara Mua Future Streets
Shifting short trips by car to walking and cycling would bring large benefits for health and fairness in cities.Funding proposalsRedefining the social construct of depression through Samoan views.
As an undergraduate student taking a bachelor of health science, I have developed a great interest in the health issues I have explored in my papers about Pasifika health issues.Funding proposalsPrecision treatment of head and neck cancer with evofosfamide
Tumour hypoxia is a major problem in head and neck cancer, promoting cancer growth and resistance to therapy, but providing an opportunity for tumour-selective therapeutic targeting.Funding proposalsDo concomitant medicines impede safe and effective lung cancer treatment in NZ?
Lung cancer is the biggest cancer killer in NZ. Recently, new, personalised, lung cancer treatments were introduced in NZ that have begun to reduce cancer deaths.Funding proposals