3304 Results
Measuring perceived task difficulty during rehabilitation
Getting better at tasks like walking, speaking and planning daily activities can improve a person’s quality of life after stroke. Research suggests that there is an optimal level of difficulty or challenge point where learning is greatest.Funding proposalsEnhancing balance in older adults via noisy Galvanic Vestibular Stimulation
As we get older our balance deteriorates and risk of falling increases, whilst there are many possible reasons for this it is commonly associated with poor postural control and reduced capacity to integrate multiple sensory inputs in the Central Nervous SyFunding proposalsValuing health-related quality of life in New Zealand
The valuation of health states is of public health significance in NZ. At present, NZ health agencies and researchers use the EQ-5D-3L (a health-related quality of life (HRQoL) tool) to help decide which medicines and health technologies to fund.Funding proposalsWhakahā o Te Pā Harakeke
The Whakahā o Te Pā Harakeke programme represents a collaboration that will develop and improve evidence designed to close smoking disparities, particularly for Māori and Pasifika, enhance how tobacco control evidence is used in decision making, and acceleFunding proposalsExploring medicinal cannabis use in New Zealand in a time of policy change
Medicinal cannabis is currently used to address a range of physical and psychological conditions, often without diagnosis or professional advice.Funding proposalsSupporting mothers and babies in Lakes District
Pregnancy and the postnatal period present a key opportunity to improve maternal health and future child health particularly for Māori, who compared to non-Māori, have lower rates of childhood immunisation, lower rates of breastfeeding, and higher rates ofFunding proposalsPrediction of the form-function musculoskeletal system in a paediatric population
Childhood conditions such as developmental hip abnormalities, cerebral palsy and slipped capital femoral epiphysis can lead to complex hip and knee deformities.Funding proposalsSocial Rhythm Therapy and Bright Light for Treatment-Resistant Bipolar Disorder
Bipolar disorder (BD) is a common disease with a high burden related to frequent relapse and cognitive impairment. A significant factor in maintaining dysfunction and risk of relapse, is circadian rhythm disturbance.Funding proposalsDiet and circulating lipids in relation to cardiovascular disease in New Zealand
Over 180,000 people in New Zealand currently live with heart disease. MENZACS is a study which aims to recruit 3,000 New Zealanders who have had an first-time acute coronary syndrome.Funding proposalsHe Pātaka Marohi - The feasibility of novel and conventional instruments
The conventional field assessment of fruit and vegetable (FV) consumption is by self-report. This method is prone to error and large variances rendering it unsuitable as a primary outcome.Funding proposalsNovel approach to measuring the food and activity environments for child health
Kernel density estimation (KDE) is an emerging spatial analysis technique that takes into account both the proximity and density of features of the environment (e.g. parks, fast food outlets) in relation to each other.Funding proposalsGroup Transdiagnostic Treatment for Anxiety and Depression in Primary Care
Anxiety and depression are the most common mental health presentations in primary care and are currently treated by individual CBT-informed sessions by brief intervention counsellors. This may not be the most effective or efficient model of treatment.Funding proposalsReducing the burden of knee osteoarthritis through community pharmacy
Knee osteoarthritis (OA) is a common and disabling condition. Knee OA affects hundreds of thousands of New Zealanders and costs NZ billions of dollars each year.Funding proposalsOxygen control in 3D-bioprinted osteochondral constructs
Nearly 17% of New Zealanders suffer from osteoarthritis, causing significant amount of pain, disability and economic burden ($3.2billion/year).Funding proposalsHe Maunga Pakohe Rautaki Hauora
Ngati Kuia Te Iwi Pakohe are seeking to undertake research that will enable us to develop a significant piece of work focussing on an overarching Hauora Strategy, He Maunga Pakohe Rautaki.Funding proposalsYoung Maori women and long-acting reversible contraception (LARC): Identifying barriers to access in primary health care
This project identifies the health system barriers and enablers that young Ma¯ori women in the Counties Manukau region experience when seeking access to long-acting reversible contraception (LARC).Funding proposalsAberrant purinergic afferent signalling in cardiovascular disease
Cardiovascular disease often occurs due to high blood pressure (hypertension), which affects one third of New Zealanders. Alarmingly, despite taking medication 50% of patients remain hypertensive. We urgently need a new way to control blood pressure.Funding proposalsAssessing the impact of maternal and perinatal interventions on life-long health
Randomised trials are the gold standard for assessing which new treatments, including those in early life, are the most effective for improving life-long health.Funding proposalsARCOS V: Incidence of stroke and TIA in NZ
Stroke is the 2nd most common cause of death worldwide, with 9000 strokes occurring in New Zealand (NZ) annually.Funding proposalsTangata Whenua Tangata Ora: Investigating health gain through whenua initiatives
This programme will investigate whenua initiatives that aim to produce health gains.Funding proposalsDeveloping computational tools to design highly potent antibiotics
There is an urgent need to develop novel antibiotics due to the rise of multidrug-resistant (MDR)-bacteria globally.Funding proposalsDoes energy deficiency compromise myofilament contractility in diabetes?
The leading cause of death for people suffering from type 2 diabetes is heart disease. The ability of the diabetic heart to pump blood around the body is diminished.Funding proposals“Missing Women” in New Zealand: Exploring Gender Bias in Migrant Communities
We aim to conduct original research in New Zealand on excess female mortality in-utero and in infancy in ethnic minority communities.Funding proposalsNext-generation cardiac ultrasound: training echocardiography using MRI
Cardiac ultrasound is the most common way to look at and measure heart function. It is used to detect many different types of heart disease, and to guide treatment once heart disease is detected.Funding proposalsThe ‘Surgical Canary’ : A Rapid Detector of Anastomotic Leaks
Colorectal surgery is commonly performed for diverse indications, and most commonly for colorectal cancer. The most serious risk of colorectal surgery is 'leaks' from the surgical join.Funding proposalsRebalancing fluid distribution in critical illness
Acute critical illness is often associated with the development of oedema (tissue swelling). The basis for this relates to an imbalance between blood-derived fluid delivery to the tissues and its subsequent clearance by capillaries and lymphatics.Funding proposalsEnabling New Zealand biomedical research with superior targeted cell ablation models
Numerous research teams around New Zealand employ targeted cellular ablation models to study physiology and degenerative disease. Many of these models are flawed, exhibiting confounding off-target toxicities, insufficient killing of target cells, or both.Funding proposalsDevelopment of a non-invasive diagnostic test for endometriosis
Endometriosis is a chronic and debilitating condition and the most common cause of morbidity and infertility in women. It is characterised by the presence and growth of endometrium (womb lining) outside the womb.Funding proposalsInvestigating iNKT Cell-Based Vaccinology to Treat Drug Addiction
Drug addiction imposes an enormous burden on health, welfare and law enforcement both in New Zealand and worldwide. The social cost of drug-related harm in New Zealand is estimated at $1.8b annually.Funding proposalsTransforming the paradigm of functional genome organisation
Within the nucleus, genomic DNA is exquisitely packaged with proteins creating highly folded yet dynamic fibers of chromatin.Funding proposalsAsthma - a test case for precision
How mutations associated with asthma impact on the genes that are switched on and co-morbidity with other disorders (e.g. type 1 diabetes) is gradually being understood.Funding proposalsA novel device for early cancer detection
Cancer survival would be transformed if it could be routinely detected at an early stage. This is currently not possible for most cancers due to the absence of markers with sufficient sensitivity and specificity.Funding proposals