2305 Results
A clinical:research alliance for diagnosing genetic disorders in New Zealand
Human genetics has been transformed by the advent of high-throughput sequencing, and many countries have instigated national initiatives to deliver clinical-based exome sequencing as a first-tier test, often with a strong preclinical arm to drive further vFunding proposalsScoping an online ‘research ready’ lifestyle programme for type-2 diabetes
Type-2 diabetes (T2D) is an inequitable health burden in New Zealand.Funding proposalsImproving blood safety and donor selection
Our medical care relies on a safe, sufficient blood supply. This project, in partnership with the NZ Blood Service (NZBS), seeks to minimise risk to the blood supply while maximising blood donations.Funding proposalsReflecting informed choice in population screening: Progressing equity
Population screening programmes begin with an invitation to participate.Funding proposalsCryopreserved vs. Liquid Platelets for Surgical Bleeding (CLIP-II NZ)
Bleeding after major surgery, traumatic injury or associated with medical conditions can be life threatening.Funding proposalsAssessing the oral health sector’s organisational commitment to equity
Equity is a key priority of NZ’s health system, and for Māori, a constitutional right. Yet, severe, unacceptable and avoidable disparities in oral health persist.Funding proposalsDeveloping a pathway of care for carpal tunnel syndrome
Carpal tunnel syndrome (CTS) affects one in 10 people at some point, causing pain, loss of feeling, interfering in daily function, sleep, and work. Untreated CTS can result in permanent nerve damage and impaired hand function.Funding proposalsCT to reduce invasive coronary angiography in acute coronary syndrome
Currently, most patients admitted to hospital with a presumed heart attack (acute coronary syndrome) remain in hospital until an invasive test can be done involving a tube and dye being inserted into the heart’s arteries (a coronary angiogram).Funding proposalsImproved Surgical Scheduling Software
The aim is to develop software that schedules elective surgical sessions quickly and in a way that reduces the chances of the sessions running overtime.Funding proposalsLooking at the placenta through a detailed lens: relating anatomy to function
When a fetus does not grow as well as it should, it can have major implications that last a lifetime. Unfortunately, many cases of fetal growth restriction are not detected early in pregnancy, when problems start to occur.Funding proposalsVaccine development: upping the ante
To be effective, vaccines need to engage both the adaptive and innate arms of the immune system. This, in turn, requires a vaccine to contain an antigen (i.e.Funding proposalsImproving primary care service delivery for those impacted by violence
Intimate partner violence is a key determinant of ill-health poorly recognised at policy and practice levels within the New Zealand health system.Funding proposalsIntervening in sleep to improve perinatal mental health outcomes
The overarching aim of this research is to improve perinatal mental health in New Zealand through sleep and circadian health education and intervention.Funding proposalsAccess to medicines: Exploring lived experience to inform policies and programmes
Medicines are extremely important for treating illness and for keeping people healthy. Yet many groups of people miss out on medicines they need, or do not use them appropriately.Funding proposalsReducing inequities in Well Child Tāmariki Ora developmental surveillance
Inequities in learning, development and health are evident when children start school. These trajectories track into adulthood with consequent poorer educational, health and social outcomes.Funding proposalsImplementing HPV primary testing to prevent cervical cancer in NZ: Te Tai Tokerau
The World Health Organization has called for the global elimination of cervical cancer. Two major technologies will contribute to this aim. The first is HPV vaccination, which is already offered to all adolescents through the school vaccination programme.Funding proposalsSleep problems in children with a mild traumatic brain injury
Good quality sleep health is fundamental for children’s optimal developmental outcomes.Funding proposalsDelivering optimal weight gain advice to pregnant women (DOT) study
Excess gestational weight gain (GWG) increases the risk of adverse outcomes for mother and baby, e.g. gestational diabetes, postpartum weight retention, and large for gestational age babies.Funding proposalsSocial response to COVID-19 in New Zealand: Obligations and stigmatisation
The proposed research will investigate the social response to the presence of COVID-19 in NZ. It is two-fold.Funding proposalsImproving effectiveness and equity in the operation of COVID-19 ‘self-isolation’
Self-isolation and quarantine have become a key part of New Zealand’s border controls and containment strategy against COVID-19.Funding proposalsTowards a national, equitable & sustainable clinical trial system in Aotearoa NZ
We have assembled a national team of experts, plus a broad stakeholder group and international advisory panel, to investigate the clinical trials landscape across Aotearoa New Zealand. We will utilise existing data sources plus direct retrieval from organiFunding proposalsConvergence of gaming and gambling in treatment services
Internet gaming disorder (IGD) is now recognised by the World Health Organization as a source of harm especially among young people. In New Zealand, we know almost nothing of the extent of IGD harm and there are no accessible treatment options.Funding proposalsDistinguishing COVID-19 from influenza with rapid 15 minute diagnostics
Diagnostic testing is critical for the containment of COVID-19 and other infectious diseases. Due to the current complexity of the tests and thus capacity limits, testing is typically limited to those meeting certain threshold criteria.Funding proposalsPredict and Prevent COVID-19: a data driven innovation project
The study of how infectious diseases like COVID-19 spread and how well public health interventions and therapies work is suboptimal.Funding proposalsCorrelating digital image features of breast cancer nuclei with molecular data
A critical component in predicting how breast cancers are likely to behave and whether treatments such as chemotherapy are required, is the tumour grade.Funding proposalsRongo-ā-Ngāti Hine: Development of a Rongoā Māori Strategic Plan for Ngāti Hine
This project aims to develop a Rongoā Māori (traditional Māori healing) strategic plan for Ngāti Hine Iwi. There is a growing need to respond to whānau demands for access to rongoā Māori.Funding proposalsEconomic Risks from COVID-19 in Pacific Island Countries
We measure the overall economic risk that is associated with COVID-19 in Pacific Island Countries (PICs). Based on work developed in Noy et al.Funding proposalsRapid diagnosis and genome sequencing to follow CoV-2019 outbreak
Rapid diagnosis of SARS-CoV-2 is critical for slowing the spread of the virus. Here we propose developing streamlined protocols for virus detection and genome sequencing.Funding proposalsAn effective point-of-care screening pathway for COVID-19
We will develop a test and workflow in partnership with rural Māori communities and primary care providers to screen patient samples for COVID-19 at the point-of-care (e.g. doctors clinic, airports). If robust, this is a front-line triage tool.Funding proposalsClinical trial of COVID-19 treatments for the critically ill
An existing study evaluating multiple treatments for severe pneumonia ("REMAP-CAP") is currently active in over 70 ICUs worldwide, including 10 sites in NZ.Funding proposalsCOVID-19 Pandemic in Aotearoa NZ: Impact, Inequalities & Improving our response
The goal of this project is to guide an effective and fair pandemic response in Aotearoa New Zealand. Experience from overseas demonstrates the profound impact of the COVID-19 pandemic on populations.Funding proposalsAustralasian COVID-19 Trial (ASCOT)
ASCOT is an open label randomised controlled trial of unproven treatments for pandemic coronavirus infection among people unwell enough to need admission to hospital, but not so unwell that they need intensive care.Funding proposals