2305 Results
Designing a scalable vaccine to induce liver resident T cells against malaria
Our preliminary data in animals have shown that long-lived protective immunity against the infectious Plasmodium species that cause malaria can be elicited with vaccines that induce parasite-specific T cells that form a resident population in the liver.Funding proposalsImproving Health Care for Cook Islands people with Chronic Kidney Disease
We will interview Cook Islands people with chronic kidney disease (CKD) and the providers of health services to investigate the care pathways for patients with CKD.Funding proposalsPsychological effects of the March 15 Mosque attacks
The Christchurch Mosque attacks are one of the worst mass shootings in history.Funding proposalsLow-intensity therapy and parent coaching for young children with ASD: An RCT.
Research suggests that 20 or more hours per week of intervention over several years may lead to significant improvements in long-term outcomes for young children with autism spectrum disorder (ASD).Funding proposalsA human functional genomics approach to investigate inflammation in dementia
Dementia is a debilitating disorder for both patients and their carers. Unfortunately the prevalence of this disease is increasing in New Zealand.Funding proposalsInterrogating immunotherapy for dental pulp therapy and management
Dental caries is a prevalent chronic disease that affects one in three adults in New Zealand. Caries destroys tooth structure and will progress to dental pulp infections and pain.Funding proposalsACTION-TBI: ACT to improve recovery after Traumatic Brain Injury
Nearly half of people who experience a mild brain injury, also known as concussion, experience on-going symptoms and difficulties functioning in everyday life. Treatment is currently provided by ACC and includes provision of psychological support.Funding proposalsPreoperative exclusive enteral nutrition versus usual care in Crohn's disease
Many patients with Crohn’s disease, an inflammatory bowel disease, will require gastrointestinal surgery to remove diseased parts of their bowel.Funding proposalsMetabolites in plasma and urine as objective markers of dietary intakes
Although the impact of diet on health and disease is unquestionable, most of what we know about habitual diet is derived from self-reported dietary intakes.Funding proposalsTAONGA - Tōku Ara OraNGA: a Kaupapa Māori informed co-design of outpatient care
Thyrotoxicosis is a common endocrine disorder. Untreated, it leads to significant illness, reduced quality of life and premature death. Māori have an increased incidence of thyrotoxicosis.Funding proposalsSexual and Reproductive Health Education among Pacific Youth
The project aims to examine and develop culturally responsive sexual and reproductive health (SRH) education for Pacific Youth in New Zealand and will be based on the experiences of Pacific youth, community and sexual and reproductive health educators in aFunding proposalsPsychosocial wellbeing after stroke: Understanding and enhancing care
Psychosocial wellbeing is important for living well after stroke. It has four dimensions: a sense of pleasure, engagement in meaningful activities, good social relationships and a strong self-identity.Funding proposalsTele-mental health delivery of psychotherapy for recurrent mood disorders
This project aims to evaluate the feasibility of delivering psychotherapy for recurrent mood disorders via teleconferencing.Funding proposalsThe Māori in-between? Identity, health, and social service access needs
Nō hea koe? Translated as “where are you from?” is a common question in Te Ao Māori. In the answer, one expresses their identity links to people, places, and Iwi.Funding proposalsNovel non-invasive neuromodulation treatment for chronic low back pain
Chronic low back pain (CLBP) is a disabling condition worldwide, associated with huge economic costs.Funding proposalsTaking a break from Netflix: The effect on glycaemia and sleep
We spend most of our day sitting. Sitting has been associated with increased risk of diseases such as diabetes but performing regular activity breaks (~2 min of activity every 30 min) throughout the day can help to reduce this risk.Funding proposalsCalsequestrin as a target to restore calcium balance in atrial fibrillation
Atrial fibrillation (AF) is a serious condition in which there is abnormal rhythm in the atria of the heart. This increases the risk of stroke, with AF patients having a high mortality rate and reduced quality of life.Funding proposalsTe Poipoia Tūkino o Hauraki - courageous conversations about safety
This funding will enable an established Women's Refuge to develop, and, submit a Ngā Kānohi Kitea project application.Funding proposals'Mā wai e tō taku kauwae ki uta' - who will take my place?
Initial findings of Ngati Pikiao Iwi Trust’s research into the positive aging of Ngati Pikiao (NP) peoples indicates that kōeke (elders) fulfilling paepae (marae cultural) duties are tired.Funding proposalsTe Puna Taiao - improving health outcomes for tamariki
The purpose of the research is to contribute to generating an evidence base around improving health outcomes for tamariki Māori through enrichment and best use of primary school natural envionments for the benefit of tamariki, their whānau and communities.Funding proposalsHealthy & safe truck drivers, safer journeys: feasibility of a national survey
In the aftermath of the catastrophic Pike River Mine explosion New Zealand's poor workplace health and safety record has been under scrutiny. Truck drivers are a neglected occupational group.Funding proposalsKimi Ora - Investigating the scalability of a diabetes intervention for Maori
Kimi Ora is a diabetes intervention programme that was developed as part of the Healthier Lives National Science Challenge by He Pikinga Waiora.Funding proposalsSYMBIOTIC: Integrated prevention of infectious diseases and long-term conditions
Poverty, infectious diseases, and serious long-term conditions such as stomach cancer and diabetes tend to occur together (termed ‘syndemics’).Funding proposalsImproving equitable access to diabetes eye services
1 in 20 New Zealanders have diabetes, and Māori and Pacific people are more likely than other New Zealanders to experience diabetes and its complications.Funding proposalsThe epidemiology of Crohn’s and Colitis in New Zealand: a data linkage study
Crohn’s disease and ulcerative colitis are Inflammatory Bowel Diseases (IBD) affecting approximately 20,000 New Zealanders, a number expected to double by 2026.Funding proposalsComprehensive pan-cancer characterization of uncommon TP53 mutations
There is a continuous need to identify patients with aggressive disease and therapies they are most likely to benefit from. p53 is known as the “guardian of the genome” and is a commonly mutated gene in cancer.Funding proposalsexciteBCI telerehabilitation: determining optimal dose and testing feasibility
Despite improvements in the prevention and acute management of stroke the number of strokes is projected to increase by 40% over the next ten years.Funding proposalsTē 'ākirāta mārama: Cook Islands mental health prevalence
Positive mental health outcomes are a priority for the Cook Islands, with efforts in place to meet the needs of the population.Funding proposalsDecoding GWAS to combat renal disease in Māori and Pacific people
Chronic kidney disease (CKD) and gout disproportionately affect Māori and Pacific people compared to other populations in New Zealand.Funding proposalsLow-dose naltrexone as an adjunctive treatment in major depressive disorder
Globally, more than 300 million people suffer from depression; it is now the leading cause of disability worldwide.Funding proposalsNeonatal Glucose Care Optimisation (NeoGluCO) Study
Approximately 15% of all babies or 10,000 per annum in New Zealand develop hypoglycaemia (low blood glucose) after birth, of whom 20% require admission to neonatal intensive care for severe or recurrent hypoglycaemic episodes.Funding proposalsResveratrol – a potential novel treatment for bronchiectasis
Bronchiectasis is a debilitating chronic respiratory condition characterised by repeated chest infections and intense airway inflammation.Funding proposals