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HRC Research Repository

This library contains details of HRC-funded studies over the past 10 years, including study title, lay summary, lead investigator, host organisation, the sum awarded, year of study commencement, and contract duration.
  • Improving genetic health through RNA diagnostics

    Year:
    2022
    Approved budget:
    $1,190,889.97
    Researchers:
    Professor Logan Walker
    ,
    Professor Amanda Spurdle
    ,
    Dr Grace Walker
    ,
    Professor Bridget Robinson
    ,
    Dr John Pearson
    ,
    Dr Richard King
    ,
    Dr Vanessa Lau
    ,
    Dr Michaela Pettie
    Host:
    University of Otago
    Proposal type
    Project
  • Is Exendin-4 neuroprotective after perinatal hypoxia-ischaemia?

    Year:
    2022
    Approved budget:
    $1,199,443.45
    Researchers:
    Associate Professor Joanne Davidson
    ,
    Professor Alistair Gunn
    ,
    Professor Laura Bennet
    Host:
    The University of Auckland
    Proposal type
    Project
  • Bringing precision to the diagnosis of complex neurodevelopmental disorders

    Year:
    2022
    Approved budget:
    $1,199,831.41
    Researchers:
    Professor Stephen Robertson
    ,
    Dr Laura Gumy
    ,
    Associate Professor Phillip Wilcox
    ,
    Professor Magdalena Goetz
    ,
    Professor Paul Lockhart
    ,
    Professor Rick Leventer
    Host:
    University of Otago
    Proposal type
    Project
  • What does dementia mean for Pacific communities in New Zealand?

    Year:
    2022
    Approved budget:
    $1,193,620.50
    Researchers:
    Dr Fuafiva Fa'alau
    ,
    Professor Vili Nosa
    ,
    Dr John Sluyter
    ,
    Dr Makarena Dudley
    ,
    Dr Malakai Ofanoa
    ,
    Mrs Mayor Pokino
    Host:
    The University of Auckland
    Proposal type
    Pacific Health Project
  • Hormones and mood: Imaging the impact of obesity on maternal neural circuitry

    Year:
    2022
    Approved budget:
    $1,199,908.32
    Researchers:
    Dr Rosemary Brown
    ,
    Professor David Grattan
    ,
    Isaiah Cheong
    Host:
    University of Otago
    Proposal type
    Project
  • Regulating retail vaping to support smoking cessation

    Year:
    2022
    Approved budget:
    $1,199,839.52
    Researchers:
    Professor Christopher Wilkins
    ,
    Professor Janet Hoek
    ,
    Dr Alexander Schnack
    ,
    Associate Professor Geoff Kira
    ,
    Professor El-Shadan Tautolo
    ,
    Dr Jude Ball
    ,
    Associate Professor Marta Rychert
    ,
    Dr Penelope Truman
    ,
    Dr Jose Romeo
    ,
    Dr Stefania Mattea
    Host:
    Massey University
    Proposal type
    Project
  • Activity of orexigenic AgRP neurons during pregnancy and lactation

    Year:
    2022
    Approved budget:
    $1,197,681.24
    Researchers:
    Professor David Grattan
    ,
    Dr Sharon Ladyman
    ,
    Ms Penelope Knowles
    Host:
    University of Otago
    Proposal type
    Project
  • Immune cells, bacteria and epithelium in Crohn's disease patients

    Year:
    2022
    Approved budget:
    $1,190,405.53
    Researchers:
    Professor Roslyn Kemp
    ,
    Professor Dr Michael Schultz
    ,
    Dr Safina Gadeock
    ,
    Dr Xochitl Morgan
    ,
    Dr Andrew Highton
    ,
    Dr Ella Iosua
    ,
    Dr Lisa Fan
    ,
    Professor Robin Turner
    Host:
    University of Otago
    Proposal type
    Project
  • Is acute rheumatic fever primarily caused by scabies? A case-control study.

    Year:
    2022
    Approved budget:
    $1,189,100.15
    Researchers:
    Dr Gerhard Sundborn
    ,
    Dr Simon Thornley
    ,
    Dr Natalie Hopoi
    ,
    Dr Arthur Morris
    ,
    Dr Cielo Pasay
    ,
    Dr Daniel Engelman
    ,
    Dr Rachel Roskvist
    ,
    Noela Dugu
    ,
    Miss Loma Veatupu
    Host:
    The University of Auckland
    Proposal type
    Pacific Health Project
  • Evaluating a bedside high-sensitivity troponin within a rural chest pain pathway

    Year:
    2022
    Approved budget:
    $1,199,642.01
    Researchers:
    Dr Rory Miller
    ,
    Professor Garry Nixon
    ,
    Honorary Professor Martin Than
    ,
    Professor John Pickering
    ,
    Associate Professor Rawiri Keenan
    ,
    Professor Timothy Stokes
    ,
    Associate Professor Katharina Blattner
    ,
    Dr Jesse Whitehead
    ,
    Dr Marc Gutenstein
    ,
    Mr Joel Pirini
    ,
    Mr Talis Liepins
    ,
    Associate Professor Gerard Devlin
    ,
    Mrs Michelle Smith
    ,
    Mr Tim Norman
    ,
    Dr Jack Haywood
    Host:
    University of Otago
    Proposal type
    Project
  • Targeted immune stimulants to hypersensitise lung cancer to checkpoint blockade

    Year:
    2022
    Approved budget:
    $1,199,922.40
    Researchers:
    Associate Professor Adam Patterson
    ,
    Associate Professor Jeff Smaill
    ,
    Professor Ian Hermans
    ,
    Dr Victoria Jackson-Patel
    ,
    Associate Professor George Laking
    ,
    Dr Amir Ashoorzadeh
    ,
    Professor Robert Anderson
    Host:
    The University of Auckland
    Proposal type
    Project
  • Role of polarized exocyosis in infection of host cells by pathogenic E. coli

    Year:
    2022
    Approved budget:
    $1,199,984.57
    Researchers:
    Associate Professor Keith Ireton
    ,
    Associate Professor Joanna Kirman
    ,
    Associate Professor Mihnea Bostina
    Host:
    University of Otago
    Proposal type
    Project
  • A single-cell transcriptomic approach to gastric cancer heterogeneity

    Year:
    2022
    Approved budget:
    $1,199,413.46
    Researchers:
    Professor Parry Guilford
    ,
    Professor Michael Black
    Host:
    University of Otago
    Proposal type
    Project
  • Caffeine to improve neurodevelopmental outcomes in infants born late preterm

    Year:
    2022
    Approved budget:
    $1,439,268.95
    Researchers:
    Professor Jane Alsweiler
    ,
    Dr Christopher McKinlay
    ,
    Associate Professor Liza Edmonds
    ,
    Dr Braden Te Ao
    ,
    Dr Alana Cavadino
    ,
    Ms Jennifer Rogers
    ,
    Dr David McNamara
    Host:
    The University of Auckland
    Proposal type
    Project
  • A vaccine for Staphylococcus aureus

    Year:
    2022
    Approved budget:
    $1,199,789.30
    Researchers:
    Professor John Fraser
    ,
    Dr Fiona Radcliff
    ,
    Dr Ries Langley
    Host:
    The University of Auckland
    Proposal type
    Project
  • Targeting metabolic dysregulation to eradicate drug resistant M. tuberculosis

    Year:
    2022
    Approved budget:
    $1,199,544.36
    Researchers:
    Dr Matthew McNeil
    ,
    Associate Professor Michael Berney
    ,
    Professor Mark Hampton
    ,
    Professor Gregory Cook
    Host:
    University of Otago
    Proposal type
    Project
  • The evaluation of treatment outcomes for methamphetamine dependence in Aotearoa

    Year:
    2022
    Approved budget:
    $1,199,839.40
    Researchers:
    Associate Professor David Newcombe
    ,
    Professor Jane Sheridan
    ,
    Professor Natalie Walker
    ,
    Dr Braden Te Ao
    ,
    Dr Rodrigo Ramalho
    ,
    Professor Vili Nosa
    ,
    Ms Varsha Parag
    Host:
    The University of Auckland
    Proposal type
    Project
  • WNT signalling - a matter of degradation

    Year:
    2022
    Approved budget:
    $1,199,533.94
    Researchers:
    Professor Catherine Day
    ,
    Professor Julia Horsfield
    ,
    Professor Peter Mace
    ,
    Dr Claudia Rossig
    Host:
    University of Otago
    Proposal type
    Project
  • Development of safe, non-addictive pain medications

    Year:
    2022
    Approved budget:
    $1,199,999.90
    Researchers:
    Associate Professor Bronwyn Kivell
    ,
    Professor Thomas Prisinzano
    ,
    Katya Sellen
    Host:
    Victoria University of Wellington, Research Trust of
    Proposal type
    Project
  • Exploring a twin-track approach to violence elimination for disabled women

    Year:
    2022
    Approved budget:
    $791,757.20
    Researchers:
    Associate Professor Brigit Mirfin-Veitch
    ,
    Associate Professor Patsie Frawley
    ,
    Dr Kelly Tikao
    ,
    Dr Debbie Hager
    ,
    Dr Robbie Francis Watene
    ,
    Ms Umi Asaka
    ,
    Ms Eden Tuisaula Cruice
    ,
    Ms Aroha Mules
    Host:
    Donald Beasley Institute
    Proposal type
    Project
  • Understanding the impact of rurality on health outcomes and healthcare delivery

    Year:
    2022
    Approved budget:
    $1,199,916.05
    Researchers:
    Professor Garry Nixon
    ,
    Associate Professor Gabrielle Davie
    ,
    Professor Dr Sue Crengle
    ,
    Dr Jesse Whitehead
    ,
    Professor Dr Ross Lawrenson
    ,
    Dr Jason Tuhoe
    ,
    Ms June Atkinson
    ,
    Mr Brandon de Graaf
    ,
    Professor Peter Crampton
    ,
    Dr Allamanda Faatoese
    ,
    Mr Talis Liepins
    ,
    Mr William Leung
    ,
    Associate Professor Katharina Blattner
    ,
    Dr Rory Miller
    ,
    Professor Timothy Stokes
    ,
    Mrs Michelle Smith
    Host:
    University of Otago
    Proposal type
    Project
  • Overcoming antibody-drug conjugate resistance in HER2-positive breast cancer

    Year:
    2022
    Approved budget:
    $1,199,994.80
    Researchers:
    Associate Professor Stephen Jamieson
    ,
    Dr Euphemia Leung
    ,
    Dr Barbara Lipert
    ,
    Dr Tet-Woo Lee
    ,
    Dr Moana Tercel
    ,
    Dr Kimiora Henare
    ,
    Dr Iman Kavianinia
    Host:
    The University of Auckland
    Proposal type
    Project
  • Critical evaluation of a tumour-targeted cancer therapy for clinical development

    Year:
    2022
    Approved budget:
    $1,199,489.20
    Researchers:
    Associate Professor Jeff Smaill
    ,
    Associate Professor Adam Patterson
    ,
    Dr Victoria Jackson-Patel
    ,
    Dr Peter Fong
    Host:
    The University of Auckland
    Proposal type
    Project
  • The nGVS study for bilateral vestibular disorders

    Year:
    2022
    Approved budget:
    $1,111,603.20
    Researchers:
    Professor Denise Taylor
    ,
    Dr Rachael Taylor
    ,
    Professor Paul Smith
    ,
    Associate Professor Yiwen Zheng
    ,
    Dr Usman Rashid
    ,
    Mrs Ruth McLaren
    ,
    Ms Misty Edmonds
    Host:
    Auckland University of Technology
    Proposal type
    Project
  • Climate change, heat exposure and child health

    Year:
    2022
    Approved budget:
    $1,199,999.10
    Researchers:
    Dr Hakkan Lai
    ,
    Professor Simon Hales
    ,
    Associate Professor Annabel Ahuriri-Driscoll
    ,
    Dr Tina Newport
    ,
    Dr Luke Harrington
    ,
    Dr Jeong Eun Lee
    ,
    Dr Annette Bolton
    ,
    Professor Dr Susan Morton
    ,
    Professor Alistair Woodward
    Host:
    The University of Auckland
    Proposal type
    Project
  • A dual-safety system to promote CAR T cell activation and migration

    Year:
    2022
    Approved budget:
    $1,199,975.45
    Researchers:
    Professor Alexander McLellan
    ,
    Professor Phil Darcy
    Host:
    University of Otago
    Proposal type
    Project
  • ARISE FLUIDS Aotearoa Randomised Controlled Trial

    Year:
    2022
    Approved budget:
    $1,199,949.75
    Researchers:
    Associate Professor Peter Jones
    ,
    Nina Baker
    ,
    Professor Paul Young
    ,
    Dr Colin McArthur
    ,
    Honorary Professor Martin Than
    ,
    Professor Papaarangi Reid
    ,
    Dr Kim Yates
    ,
    Dr Eunicia Tan
    ,
    Dr Anna Vosseteig
    ,
    Dr Robert Martynoga
    ,
    Dr Michael Connelly
    ,
    Dr Matthew Moore
    ,
    Professor Christopher Frampton
    ,
    Dr Alisa Higgins
    ,
    Dr Stephen MacDonald
    ,
    Professor Stuart Dalziel
    Host:
    Medical Research Institute of New Zealand
    Proposal type
    Project
  • Spatial profiling of tumour tissue to improve lung cancer immunotherapy

    Year:
    2022
    Approved budget:
    $1,200,000.35
    Researchers:
    Professor Rod Dunbar
    ,
    Dr Saem Park
    ,
    Dr Kimiora Henare
    ,
    Associate Professor Klaus Lehnert
    ,
    Dr Laird Cameron
    ,
    Dr Michael Lau
    Host:
    The University of Auckland
    Proposal type
    Project
  • HCQ4ARF: A randomised trial of Hydroxychloroquine for acute rheumatic fever

    Year:
    2022
    Approved budget:
    $1,437,916.85
    Researchers:
    Associate Professor Rachel Webb
    ,
    Professor Nigel Wilson
    ,
    Dr Danny de Lore
    ,
    Dr Alexandra Wallace
    ,
    Joshua Agnew
    ,
    Dr John Malcolm
    Host:
    The University of Auckland
    Proposal type
    Project
  • Hypoxia-selective delivery of DNA-PK inhibitors to tumours

    Year:
    2022
    Approved budget:
    $1,199,999.65
    Researchers:
    Associate Professor Michael Hay
    ,
    Associate Professor Stephen Jamieson
    ,
    Dr Lydia Liew
    ,
    Dr Cho Rong Hong
    ,
    Dr Kimiora Henare
    ,
    Dr Tet-Woo Lee
    ,
    Dr Gib Bogle
    ,
    Emeritus Professor William Wilson
    Host:
    The University of Auckland
    Proposal type
    Project
  • RCT budesonide-formoterol reliever therapy in moderate/severe childhood asthma

    Year:
    2022
    Approved budget:
    $1,439,964.30
    Researchers:
    Professor Stuart Dalziel
    ,
    Professor Richard Beasley
    ,
    Professor Catherine Byrnes
    ,
    Dr David McNamara
    ,
    Professor Dr Alex Semprini
    ,
    Associate Professor Matire Harwood
    ,
    Professor Mark Weatherall
    ,
    Dr Louise Fleming
    ,
    Professor Andrew Bush
    Host:
    The University of Auckland
    Proposal type
    Project
  • Hormone-induced adaptations in respiratory function during pregnancy

    Year:
    2022
    Approved budget:
    $1,199,969.09
    Researchers:
    Professor David Grattan
    ,
    Professor Julian Paton
    ,
    Dr Teodora Georgescu
    Host:
    University of Otago
    Proposal type
    Project
  • New targets for infectious disease - tackling antimicrobial resistance

    Year:
    2022
    Approved budget:
    $1,200,000.00
    Researchers:
    Professor Emily Parker
    ,
    Dr Wanting Jiao
    ,
    Professor Peter Tyler
    ,
    Professor Gregory Cook
    ,
    Associate Professor Jeremy Lott
    ,
    Dr Gerd Mittelstadt
    ,
    Dr Matthew McNeil
    Host:
    Victoria University of Wellington, Research Trust of
    Proposal type
    Project
  • Manaaki Te Iti Kahurangi: Improving outcomes for whānau

    Year:
    2022
    Approved budget:
    $4,999,905.10
    Researchers:
    Professor Beverley Lawton
    ,
    Helmut Modlik
    ,
    Associate Professor Liza Edmonds
    ,
    Dr Kendall Stevenson
    ,
    Ms Anna Adcock
    ,
    Dr Leigh Duncan
    ,
    Associate Professor Lynne Russell
    ,
    Dr Evelyn MacDonald
    ,
    Dr Melanie Gibson
    ,
    Mrs Francesca Storey
    ,
    Dr Tania Slater
    ,
    Miss Tina Bennett
    ,
    Ms Varsha Parag
    ,
    Dr Judy Ormandy
    ,
    Ms Victoria Roper
    ,
    Ms Michelle Vincent
    Host:
    Victoria University of Wellington, Research Trust of
    Proposal type
    Māori Health Programme
  • Reducing the burden of osteoarthritis in Aotearoa New Zealand

    Year:
    2022
    Approved budget:
    $4,999,268.10
    Researchers:
    Professor J. Abbott
    ,
    Dr Ross Wilson
    ,
    Associate Professor Kirsten Coppell
    ,
    Dr Ricky Bell
    ,
    Professor Søren Skou
    ,
    Dr Kirsten Smiler
    ,
    Professor Timothy Stokes
    ,
    Dr Yana Pryymachenko
    ,
    Dr Philippa Nicolson
    ,
    Professor David Gwynne-Jones
    ,
    Ms Angeline Tangiora
    ,
    Professor Peter Choong
    ,
    Professor Kim Bennell
    ,
    Professor Rachelle Buchbinder
    ,
    Professor Deborah Marshall
    ,
    Professor Michelle Dowsey
    ,
    Dr Jackie Whittaker
    Host:
    University of Otago
    Proposal type
    Programme
  • Pathogenesis, detection and treatment of perinatal brain injury

    Year:
    2022
    Approved budget:
    $4,999,982.55
    Researchers:
    Professor Alistair Gunn
    ,
    Professor Laura Bennet
    ,
    Associate Professor Joanne Davidson
    ,
    Associate Professor Justin Dean
    ,
    Dr Hamid Abbasi
    Host:
    The University of Auckland
    Proposal type
    Programme