3304 Results
Translational advances in gastrointestinal (GI) surgical recovery and motility disorders
Disorders of gastrointestinal (GI) function inflict a vast burden of symptoms, suffering and cost on society.Funding proposalsUnderstanding genetic risk factors for metabolic disease in Maori and Pacific
Risk of diabetes and obesity and type-2 diabetes is greatly increased in Maori and Pacific people compared with other New Zealanders of European descent but the reasons for this are not fully understood.Funding proposalsOcular laser bio-meter, fast and cheap early diagnosis of vision impairment
Overall, global vision loss costed nearly $3 trillion in 2010 for the 733 million people living with low vision and blindness.Funding proposalsA unique cellular mechanism for diabetic heart disease?
Diabetes reduces the heart’s capacity and increases the incidence of heart failure dramatically.Funding proposalsDeveloping and validating a novel site for mobile and unobtrusive electro-encephalograms (EEG) recording
The brain controls everything we do. Analysis of brain activities (electro-encephalograms (EEG)), taps into the ultimate biometric, with the potential to assess every physical and mental state we experience.Funding proposalsPinpointing prostate cancer: a paradigm shift in diagnosis
Prostate cancer is the most diagnosed cancer in men, after lung cancer and New Zealand has a high incidence of both occurrence and mortality.Funding proposalsA universal scaffold for multivalent vaccine development
Infectious diseases account for 15-20% of global mortality, with the highest incidence in resource-poor settings. Vaccination against infectious disease remains the most effective medical intervention.Funding proposals'‘This is not an Intervention, It’s a Movement!’: reducing screen time in teens
Excessive screen time is a public health issue in New Zealand due to its adverse effects on the physical and socio-emotional health of teenagers. A new way of targeting this pervasive behaviour is required.Funding proposalsUsing smallpox proteins to treat human inflammation
We propose to study the set of immune modulating proteins made by the smallpox virus as a source for treatments for human inflammation.Funding proposalsIs there a ‘fourth axis’ of vesicular communication?
Human cells in our body communicate with one another through multiple pathways. One established route is via their ability to produce a range of different signalling “packages”, called vesicles.Funding proposalsTowards personalised digital health services for preventable health conditions
To improve preventive health outcomes, a radical shift in thinking needs to be introduced to understand underlying causes of people’s subconscious behaviour to provide personalised digital health services in future; especially to support people most in neeFunding proposalsEngageBOT: exploring chatbots for supporting patient engagement
There is no denying that patient engagement is a major challenge for all health care organisations; whether it is keeping them informed of changes, supporting the transition home after a health event, or responding to questions.Funding proposalsTargeting breast cancer metastasis with heparan sulfate mimetics
Human breast cancer cells express heparanase, an enzyme that degrades the extracellular matrix that surrounds cells, including tumour cells.Funding proposalsTargeting HIF-1 in triple negative breast cancer using glutaminase inhibitors
Low-oxygen (hypoxia) is a common feature of breast tumours that promotes aggressive disease outcomes and poor patient survival. Hypoxia is “sensed” in cells by a protein called hypoxia-inducible factor 1 (HIF-1).Funding proposalsInvestigating Fn14 as a driver of breast cancer metastasis
Breast cancer is the most common malignancy worldwide and the leading cause of cancer death in women. Invasion and metastasis are the major reasons for breast cancer-associated mortality.Funding proposalsPreventing breast cancer metastasis with conjugate vaccines targeting human HER2
Metastasis is a devastating complication of breast cancer, and tumours over-expressing human epidermal growth factor receptor 2 (HER2) carry higher risk. One strategy to prevent metastasis is to vaccinate against HER2.Funding proposalsSpatial variability in breast cancer incidence, care and outcomes
Disparities exist in breast cancer incidence, care and outcomes in New Zealand, imposing a disproportionate burden on Māori and Pacific women and those living in deprived or remote areas.Funding proposalsAnalysis of DCIS data in the National Breast Cancer Register
Ductal carcinoma in situ (DCIS) accounts for approximately 20% of breast cancers and represents cancer cells confined within the normal structures of the breast.Funding proposalsGaps in the provision of radiotherapy for early breast cancer
Breast cancer is the third leading cause of death for Maori and non-Maori women in New Zealand, and Maori women are more likely to develop breast cancer and to die from it than non-Maori women.Funding proposalsPertussis immunisation in pregnancy - infant outcomes
In a recent study (PIPIO Study), we found that infants born to mothers given the whooping cough vaccine in pregnancy, were at greater risk of whooping cough in the period following their own first dose of vaccine (at 6 weeks of age) than infants born to unFunding proposalsA decision aid to incorporate patient preferences into biologic therapies
Biologic therapies for rheumatoid arthritis are very effective but very costly. Recent data suggests that some people who have a good response to biologic therapies can stop these agents and maintain low levels of disease activity.Funding proposalsEvidence to guide investment in a model of primary care for all
Evidence is unclear on which models of primary care are most effective in New Zealand.Funding proposalsWhāia te Manaaki: manaakitanga and hauora for Te Atiawa ki Whakarongotai
The proposed research aims to build on results of a previous research project, Whaia Te Ahi Kaa: Ahi Kaa and its role in Oranga by exploring at a deeper level one component of ahi kaa; manaakitanga.Funding proposalsKoeke a ko ake nei towards intergenerational positive aging for Ngati Pikiao
Maori cultural knowledge is fundamental to personal and hapu-iwi health and well-being; it’s dissemination through the generations is a desirable social goal.Funding proposalsTaurite Tu- Development of falls prevention exercise programme for Maori
Te Runanga o Otakou has identified a gap in fall prevention services for Maori living in Te Runanga o Otakou takiwa.Funding proposalsSupport for gaining employment for people with a long-term condition
A robust systematic review that is contextualised for the Aotearoa / New Zealand service delivery context is crucial in order to utilise the best evidence available to develop innovative case-managed support to gain employment for people experiencing healtFunding proposalsDevelopment of cross-agency collaboration to improve employment outcomes
People who experience mental health or addiction problems are much less likely to be in employment than people who do not.Funding proposalsRandomised trial of an intervention to increase tuberculosis notifications
This cooperative research project aims to conduct a randomised trial of a tailored intervention package to increase notifications of tuberculosis by private practitioners in Bandung, Indonesia.Funding proposalsIndependent Research Organisation Funding
Funding proposalsIndependent Research Organisation Funding
The MRINZ meets the eligibility for an Independent Research Organisation as: A.Funding proposalsIndependent Research Organisation Funding
Funding proposalsIndependent Research Organisation Funding
Whakauae was established in 2005 as a unit of Te Maru o Ruahine Trust (TMORT); the contracting and service arm of Ngāti Hauiti, a small iwi located in central Rangitikei.Funding proposals