2305 Results
Platform trial optimising interventions in severe community acquired pneumonia
Community acquired pneumonia is a common cause of both hospital and ICU admissions. For many aspects of treatment for patients with severe pneumonia, clinicians are uncertain which is the best choice.Funding proposals"Improving papakainga: linking health, housing and toiora (wellbeing)"
For historical reasons, Māori have tended to live in older housing, much of it built before incremental changes to the building code began to address interior living conditions, beginning in 1979.Funding proposalsImproving child and whānau health outcomes - intervention in early life settings
The purpose of the study is to contribute to generating an evidence base around what constitutes effective early life kaupapa Māori programming for children and whānau that will lead to improved health and wellbeing outcomes in later life for tamariki andFunding proposals"Mauri ora ki te whenua, he tatai nui ki te rangi"
Ko te kaupapa o tenei rangahau ki te whakanuia a tatou matauranga Maori, hei tiketike mo tatou. Ko te maramataka he whainga mo tatou te Maori, kia hono ki te whenua, kia hono ki te rangi. E matemate ana to tatou nei Iwi, e mau riri a, e mau mamae ana.Funding proposalsKia piki te hauora: Strategies to promote wellbeing in a small Maori community
This project is based on the single hypothesis that Māori wellbeing can be enhanced by establishing and nurturing connections or experiences with taonga tuku iho.Funding proposalsImproving COPD outcomes for Maori whanau
The proposed project seeks to address critical gaps in knowledge about chronic obstructive respiratory disease (COPD), a severely debilitating lung condition, which disproportionately affects Māori.Funding proposalsUsing principles of the ‘slow movement’ to prevent obesity from birth
An increased pace of life has been identified as an important driver of childhood obesity, yet has not been pursued as a target for intervention.Funding proposalsPreclinical development of non-addictive pain medications
Chronic pain affects 1 in 6 New Zealanders, robbing them of their quality of life. Chronic pain is poorly treated with current mu-opioid medications such as morphine, which become ineffective with long-term use and have high abuse potential.Funding proposalsOne cell, two phenotypes: capturing pluripotency for tisse repair
We propose a method of in vivo tissue repair based on the modulation of cell microenvironment via the application of specific growth factor/chemical combinations to harness adult cell differentiation.Funding proposalsNutrition 2.0: Toward a food systems approach for public health nutrition
Unhealthy diets are a key contributor to mortality in New Zealand (NZ) and we are in high need for workable solutions to improve population diets. However, food is not just about health. In fact, the NZ food system is the major contributor to the economy.Funding proposalsCan we rehabilitate a reflex? A treatment protocol for the cough reflex
Neurological disease or injury can damage the cough reflex, which is critical for protecting the airway from foreign matter during swallowing.Funding proposalsIntelligent digital environment for wellbeing and healthcare
This research investigates an innovative and novel approach to the delivery of health care support to older people.Funding proposalsA novel nanosensor array for heart failure diagnosis
We propose a series of experiments to prove the utility of a novel sensor in the diagnosis of heart failure. This sensor measures molecules in the air, and can be used to measure markers of disease in breath or other body fluids such as urine.Funding proposalsDesigning diagnostic and rehabilitation landscapes for the disabled
The research will develop a New Zealand appropriate set of design parameters for a series of walking paths that both measure and track the physical progress and/or regress of the aged as well as those who are or have been physically or mentally disabled.Funding proposalsTargeting HP1 regulated pathways to suppress breast cell invasion
Metastasis is the primary cause of death in breast cancer patients as it refractory to current therapies. The first step in metastatic disease occurs when a cell invades surrounding tissue.Funding proposalsUsing CRISPR-Cas9 to predict sensitivity to trastuzumab emtansine
Over 3000 diagnoses and 600 deaths are attributable to breast cancer in New Zealand each year. One-quarter of breast cancers is driven by increased amounts of a gene called HER2, which can be targeted with the drug trastuzumab (Herceptin).Funding proposalsCollaborative fever etiology research in South East Asia
1. Collaborate to conduct Myanmar's first comprehensive severe febrile illness etiology study to improve patient management and target disease prevention efforts. 2.Funding proposalsKimihia te hauora hinengaro: pathways for Maori mental health
While some research to date has provided much needed insight into the mental health needs and subsequent service use of Maori more broadly, little is known about the prevalence of mental health disorders or service uptake in West Auckland specifically.Funding proposalsTe ohu mo Papatuanuku: contaminated site toolkit for community use
The Te Ohu Mo Papatuanuku collaboration aims to assist tangata whenua within the Ngati Awa rohe to address contamination issues on their lands.Funding proposalsHe puna reo he puna oranga whanau: Impact of urban puna reo on health & wellbeing
This research project (the project) explores the impacts of an urban based Māori Puna Reo (early childcare within a kaupapa Māori context) on the health and wellbeing of tamariki and their whānau with a specific focus on taha wairua, taha hinengaro, taha tFunding proposalsImproving child and whanau health outcomes - intervention in early life settings
The purpose of the study is to contribute to generating an evidence base around what constitutes effective early life kaupapa Māori programming for tamariki and whānau that will lead to improved health outcomes in later life (across the lifespan) for tamarFunding proposalsMahi Ngātahi - Culturally responsive ways of working together
Māori as Aotearoa New Zealand’s indigenous people and partners to the Treaty of Waitangi are entitled to experience the same level of health and wellbeing as non-Māori. However, research and growing health disparities suggest this is not the case.Funding proposalsImpact of sugar-sweetened beverage taxation in the Pacific
Given the scale of the global obesity epidemic it is critical to understand if interventions to control obesity are effective.Funding proposalsDeciphering gender and ethnic disparity in obesity and cardiometabolic disease
New Zealand has the third highest rates of obesity in the world. Despite decades of effort to reduce these rates, they continue to rise, particularly in young women and especially amongst Māori and Pacific.Funding proposalsPrevention and treatment of fever in the ICU
Many critically ill patients are unable to respond to the demands that fever places on the body. One potential way to protect patients from the adverse clinical effects of fever is to systematically prevent and treat fever.Funding proposalsImpact of built environment interventions on children's physical activity
I have a cohesive research programme directed at understanding socio-environmental associates and predictors of children’s activity and body size.Funding proposalsThe effects of comorbidity on breast cancer care and outcomes
Dr Melissa Edwards is a general surgical trainee undertaking a PhD in Surgery on the impacts of comorbidity on breast cancer care and outcomes in New Zealand women. The co-existence of breast cancer and chronic concomitant disease/s is not uncommon.Funding proposalsImproving outcomes for support workers in aged care
I am a young researcher passionate about aged care. My intention is to put my stake in the ground and become an expert in this important area.Funding proposalsThe rectosigmoid brake and its utility as a neuromodulation target
Colon motility disorders and faecal incontinence are common and have a significant financial burden and impact on the quality of life. However we have limited knowledge of human colon motor patterns.Funding proposalsGeographic and ethnic inequities in stroke outcomes
Stroke is the third most common cause of death and the most significant cause of adult disability in New Zealand. We know of several key interventions that reduce disability after stroke.Funding proposalsDementia and Parkinson's disease: tau pathology and cerebrovascular health
Many people with Parkinson’s develop cognitive problems and, eventually, dementia. We need to identify suitable objective tools that measure the underlying brain changes associate with cognitive decline.Funding proposalsNovel osteoprogenitor cell populations involved in bone healing
Bone tissue is constantly replaced throughout life in a process known as remodelling. Bones also have a remarkable capacity to heal following fracture.Funding proposals