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A universal scaffold for multivalent vaccine development

35 months
Approved budget:
Dr Paul Young
Health issue:
Infectious disease
Proposal type:
Explorer Grant
Lay summary
Infectious diseases account for 15-20% of global mortality, with the highest incidence in resource-poor settings. Vaccination against infectious disease remains the most effective medical intervention. We will use a novel molecular ‘superglue’ we have developed to engineer vaccines that are effective against highly diversified pathogens. These multi-component vaccines spontaneously assemble themselves during manufacture. This promises to make production of vaccines much simpler, accelerating the development of more efficient vaccines.