Taunakitanga Takitini programme aims to build Aotearoa specific knowledge about supported self-management to enable those who experience greatest health inequities, that is, underserved populations living with lifelong conditions (specifically Māori and Pacific peoples, Tāngata Whaikaha (Māori with disability) and those experiencing learning (intellectual) disability) and their whānau to be supported to live the best possible life. Partnering with Māori, Pacific and disability healthcare providers we will explore service users and communities needs and aspirations for living well and what healthcare services would best support them and how. Using this knowledge, we will co-develop care models of how collaborative community healthcare professionals and kaiāwhina can support and work alongside whānau and communities to enable them to support themselves within their own context. These models will then be implemented, and outcomes evaluated. Our findings will inform policy, healthcare service and the public. We will thereby build Aotearoa specific research capacity and capability.