Lay summary
Rongoā Māori is a holistic healing system grounded in Māori knowledge, values, and philosophies. Karakia (prayer/incantation) is one of the most widely practiced forms of rongoā, often used to influence healing outcomes. This research explores the expertise and mātauranga (Māori knowledge) underpinning karakia, focusing on its role in enhancing hauora (health and wellbeing). Using a ‘research at the interface’ approach, it integrates mātauranga Māori with Western scientific methods (EEG/electroencephalography) to elevate wairua-based (spiritual) understandings of health, an essential component of Māori lived reality. By combining Indigenous knowledge with real-time physiological monitoring, the study offers a nuanced understanding of the effects of karakia across spiritual, emotional, and physiological domains. Karakia is a natural, accessible, and meaningful form of care for Māori patients, clients, and whānau. Recognising and incorporating karakia into clinical settings fosters more holistic, respectful care, improves health outcomes, and honours the commitments of Te Tiriti o Waitangi.