YouthCHAT is an electronic screening tool developed in 2016 to assess risk taking behaviour and detect mental health concerns among youth in primary care settings. This study will use an implementation science, co-design participatory research approach with mixed method design to explore the feasibility and acceptability of YouthCHAT, when tailored for use across settings with large Māori populations: nurse-led youth clinics, school-based clinics, and general practice. Roll-out will be pragmatic, starting with five nurse-led clinics, with up to 10 other clinics included over three years. The study aims to explore adaptation of YouthCHAT in different primary care settings; assess provider and youth acceptability of the tool, and identify changes in screening rates for mental health, help-seeking behaviour and brief intervention delivery. It is anticipated that YouthCHAT will be a culturally acceptable, cost-effective and time-saving screening tool within primary care settings, increasing youth mental health screening and improving access to care.