Lay summary
Lung cancer is a major contributor to illness, death and inequity in NZ. Lung cancer screening (LCS) reduces mortality among people at high-risk of developing lung cancer. The PLCOm2012 is widely used internationally to identify high-risk people. PLCOm2012 includes a US based ethnicity weighting to account for the differential risk seen in some ethnic groups. Whether this criteria is appropriate for the NZ context needs to be determined. Gender and deprivation are also associated with lung cancer but not currently included in the model. We will undertake LCS in NZ to assess how well the PLCOm2012 performs in predicting risk of lung cancer, especially for Māori, including analysis by gender and deprivation. The study will be conducted by our highly experienced Māori-led team across the Northern Region DHBs, and will include a mixed-methods implementation science assessment of acceptability of different methods of informing and inviting people to LCS.