Lay summary
Pelvic organ prolapse (POP), or the herniation of the pelvic organs into the vagina, is an incredibly common condition in women. Its incidence in Aotearoa is poorly understood and effective treatments are lacking.
My project will use genomics here in Aotearoa, and large international datasets, to uncover novel genes that contribute to the tissue strength of the pelvic floor. By recruiting wāhine in Aotearoa, I will be able to link genetic changes to protein expression in the pelvic floor and develop an understanding of POP here in Aotearoa.
Knowledge of critical proteins will be used to develop smart, biological drugs to strengthen healing of connective tissue in POP and other conditions. My POP research here in Aotearoa will also deliver much needed outreach and support to all women who may avoid medical care for POP.
My aspiration is to lead genomics-driven solutions for connective tissue disorders in Aotearoa.