Non-communicable diseases (NCDs) are the major cause of death and disability in the Cook Islands with almost 40% of all NCD-related deaths occurring prior to the age of 60. In addition, increasing numbers of Cook Islanders are presenting with issues related to mental well-being and parallel the alarming NCD rates. The Ministry of Health has identified the need for primary risk reduction and evidence suggests that early life interventions may have greater efficacy than traditional strategies. This project builds on pilot work in the Cook Islands with two primary goals. Our approach will encompass both identification of early life determinants (i.e. maternal factors) of later physical and mental well-being and also potential for early life intervention strategies aimed at breaking the NCD cycle and improving mental well-being via better understanding and self-awareness by Cook Island adolescents of factors underpinning their own health, behaviour and environment.