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Low dose aspirin for venous leg ulcers: a randomised trial

41 months
Approved budget:
Professor Andrew Jull
Health issue:
Proposal type:
Lay summary
Leg ulcers are a common, costly and debilitating condition and the burden will increase as the population ages. Venous leg ulcers (VLU) are the most common leg ulcer, can be painful, and limit work, lifestyles and activity, especially in older patients. There are few effective treatments - compression therapy (tight bandaging or stockings) helps healing, but about half the people with a VLU remain unhealed even after 12 weeks of treatment. Research suggests taking aspirin as well as using compression may speed up healing for VLU, but the current evidence is not enough to change clinical practice. We will conduct a randomised controlled trial to test whether using low dose aspirin really does speed up healing. If aspirin does speed up healing, it is an inexpensive treatment that could quickly be put into clinical practice.